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What are common symptoms of Wellbutrin withdrawal, and how to cope?

Are you considering discontinuing Wellbutrin, or have you recently stopped taking it? If you or a loved one is considering discontinuing the antidepressant Wellbutrin (bupropion), it’s important to be aware of the potential withdrawal symptoms that can arise. Knowing what to expect and how to manage the discomfort can help make your recovery as safe and comfortable as possible.

In this blog post, we’ll discuss common symptoms of Wellbutrin withdrawal and how to cope. Read on to learn more.

What is Wellbutrin withdrawal?

Wellbutrin (bupropion) is an antidepressant medication typically prescribed to treat depression, attention deficit hyperactivity disorder (ADHD), and seasonal affective disorder. It works by increasing the levels of norepinephrine and dopamine in the brain, which are associated with pleasure and reward.

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Withdrawal occurs when a person suddenly stops taking a medication they have been using for a while. This can cause a variety of symptoms, depending on the medication and how long it was taken. Withdrawal from Wellbutrin can be particularly difficult because of the way it affects brain chemistry.

When someone stops taking the drug abruptly, their body is not used to being deprived of these neurotransmitters and can experience uncomfortable physical and psychological symptoms.

What are common symptoms of Wellbutrin withdrawal?

Wellbutrin withdrawal can cause a range of symptoms that usually begin within 24-48 hours after the last dose and may continue for days or weeks. The severity of the symptoms varies depending on the individual, their dosage, and how long they were taking it. Remember that not everyone experiences all of these symptoms, and the duration of symptoms can vary significantly.

The most common withdrawal symptoms are:

  • Dizziness
  • Insomnia
  • Flu-like symptoms
  • Anxiety
  • Depression
  • Nausea
  • Irritability
woman holding her head in pain

More severe symptoms may include agitation, changes in appetite, suicidal thoughts or behavior, changes in energy levels, and extreme fatigue.

Some people also experience more intense and longer-lasting withdrawal symptoms, known as post-acute withdrawal syndrome (PAWS). This occurs when a person’s symptoms persist beyond the expected time frame, with some people reporting the symptoms persisting for several months after stopping the medication. Symptoms of PAWS can include fatigue, difficulty concentrating, memory problems, difficulty sleeping, irritability, anxiety, and depression.

Why should you consider medically assisted detox and rehab?

Withdrawal symptoms can be unpleasant, but fortunately they can be managed with treatment. Tapering off Wellbutrin over a period of time can help reduce the intensity and duration of the withdrawal symptoms. Your doctor can provide specific instructions regarding the best way to taper your dosage.

A therapist can provide valuable emotional support and advice on coping strategies to manage withdrawal symptoms. Medications such as benzodiazepines or antidepressants can be used to address specific withdrawal symptoms, such as sleep disturbances or anxiety. Additionally, counseling can be helpful during this difficult time.

two people sitting opposed to each other having a therapy session

If you are struggling with withdrawal from Wellbutrin, it is important to reach out for help from your doctor or mental health professional, who will assess your individual needs and provide tailored recommendations. Remember that while withdrawal from Wellbutrin can be difficult, effective treatments can make the process easier.

How to cope with Wellbutrin withdrawal

If you are considering tapering off Wellbutrin, it is important to understand the potential for withdrawal symptoms. Tapering off Wellbutrin is the best way to avoid a severe withdrawal reaction and can help reduce the severity of any symptoms that may occur. Tapering gradually over weeks or even months will allow your body to adjust to the decreasing dose of Wellbutrin, minimizing the impact of withdrawal.

Additionally, there are lifestyle changes that can help address the symptoms of Wellbutrin withdrawal. Eating a balanced diet and getting plenty of sleep is essential for maintaining physical and mental health. Regular exercise, socializing with friends and family, and finding enjoyable hobbies can also provide stress relief and improve mood.

Many experts recommend seeking out psychological support such as cognitive behavioral therapy (CBT), which can help patients to better manage their emotions and address any underlying mental health issues which may be contributing to their withdrawal symptoms. Other treatment methods include medications such as SSRIs (Selective Serotonin Reuptake Inhibitors) which can help to alleviate feelings of depression and anxiety associated with Wellbutrin withdrawal.


If you or someone you know is experiencing Wellbutrin withdrawal, remember that resources and treatments are available to help. Consulting a qualified healthcare professional is essential in order to get the best care and advice for your specific situation. With mobile healthcare providers becoming more and more accessible, it’s now easier than ever to receive help from a healthcare professional in the comfort of your own home. Don’t hesitate to seek out professional help if you or a loved one is struggling with Wellbutrin withdrawal.

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